Animal study about vascular ramifications of COX-2 inhibition Within an article by Egan et al, titled, Cyclooxygenases, Thromboxane, and Atherosclerosis, published in the Jan 17 issue of Circulation: Journal of the American Heart Association researchers examined some of the molecular mechanisms of drugs affecting prostaglandin and thromboxane creation. In a genetic knock-out mouse style of atherosclerosis, the experts found that the progression of atherosclerosis could possibly be slowed by a medication blocking the thromboxane receptor , however, not by inhibiting COX-1 and COX-2 with indomethacin or by inhibiting COX-2 by itself with MF tricyclic simultaneously, an experimental COX-2 inhibitor. When this COX-2 inhibitor was presented with with TP together, the atherosclerotic plaques had fewer of the characteristics associated with stable plaques ed treatments .

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Annual bone fracture rate almost 4 % and double previous estimates The annual bone fracture rate in England is just short of 4 percent of the populace, which is a lot more than twice previous estimates, suggests a scholarly research in the Journal of Epidemiology and Community Wellness. Half of middle aged guys and four out of 10 elderly females have previously sustained a fracture, the figures indicate. The findings are based on a representative population sample of more than 55,000 people, including over 10,000 people from black and minority ethnic backgrounds. Related StoriesDeben reviews on the work of the Microscopy & Histology Core Service at the University of AberdeenFracture prevention project may help save millionsNuclear medicine in Australia: an interview with Doug Cubbin, ANM Table ChairmanThe sample was extracted from individuals in the annual Wellness Survey for England , commissioned by the Department of Health.